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Objective@#To explore the value of different anastomosis methods in laparoscopic distal gastrectomy.@*Methods@#From January 2014 to January 2016, 120 patients with distal gastric cancer in Weihai Central Hospital were selected and divided into the observation group and the control group according to the random digital table method, with 60 cases in each group.Triangular anastomosis was used in the observation group, while tubular anastomosis was used in the control group.The operative conditions, pain and complications were compared between the two groups.After 1-4 years of follow-up, the prognosis of the two groups was compared.@*Results@#Compared with the control group, the operation time of the observation group was shorter[(165.2±55.2)min vs.(188.2±59.3)min], the time of anastomosis was shorter[(22.6±8.1)min vs.(29.6±9.1)min], and the amount of bleeding was less[(88.6±29.2)mL vs.(107.5±49.1)mL], the differences were statistically significant (t=2.199, 4.451, 2.563, all P<0.05). Compared with the control group, the VAS scores of 1d[(3.5±1.1)points vs.(5.2±1.9)points]and 3d[(1.9±0.7)points vs.(3.0±1.5)points] were lower in the observation group, and the differences were statistically significant (t=5.998, 5.148, all P<0.05). There was no statistically significant difference in the incidence of postoperative complications between the two groups (P>0.05). After 1-4 years of follow-up, the overall survival rates in the observation group and the control group were 72.0% and 66.0%, respectively, and the median survival time was 42.4 months and 42.9 months, respectively.There was no statistically significant difference in survival between the two groups (χ2=0.310, P>0.05).@*Conclusion@#The trigonometric anastomosis is reliable in laparoscopic distal gastrectomy for gastric cancer, and it can shorten the time of anastomosis, reduce the amount of bleeding, and improve the postoperative pain of the patients.
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Objective To explore the value of different anastomosis methods in laparoscopic distal gastrectomy.Methods From January 2014 to January 2016,120 patients with distal gastric cancer in Weihai Central Hospital were selected and divided into the observation group and the control group according to the random digital table method,with 60 cases in each group.Triangular anastomosis was used in the observation group,while tubular anastomosis was used in the control group.The operative conditions,pain and complications were compared between the two groups.After 1-4 years of follow-up,the prognosis of the two groups was compared.Results Compared with the control group,the operation time of the observation group was shorter[(165.2 ± 55.2)min vs.(188.2 ± 59.3)min],the time of anastomosis was shorter[(22.6 ± 8.1) min vs.(29.6 ± 9.1) min],and the amount of bleeding was less [(88.6 ± 29.2) mL vs.(107.5 ± 49.1) mL],the differences were statistically significant (t =2.199,4.451,2.563,all P ＜ 0.05).Compared with the control group,the VAS scores of 1d[(3.5 ± 1.1) points vs.(5.2 ± 1.9) points] and 3d [(1.9 ± 0.7) points vs.(3.0 ± 1.5) points] were lower in the observation group,and the differences were statistically significant (t =5.998,5.148,all P ＜ 0.05).There was no statistically significant difference in the incidence of postoperative complications between the two groups (P ＞ 0.05).After 1-4 years of follow-up,the overall survival rates in the observation group and the control group were 72.0％ and 66.0％,respectively,and the median survival time was 42.4 months and 42.9 months,respectively.There was no statistically significant difference in survival between the two groups (x2 =0.310,P ＞ 0.05).Conclusion The trigonometric anastomosis is reliable in laparoscopic distal gastrectomy for gastric cancer,and it can shorten the time of anastomosis,reduce the amount of bleeding,and improve the postoperative pain of the patients.
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Object This experiment was conducted to study the relationship between CFTR gene expression in the intestinal tissues and secretory diarrhea.Methods Twenty-four Kunming mice were selected, half male and half female, and were randomly divided into 3 groups ( n=8 in each group):control group with intraperitoneal injection of 0.2 mL nor-mal saline, and the experimental group of mice by intraperitoneal injection of lipopolysaccharide(LPS) (6 mg/kg· bw). The mental state and intestinal morphology of the mice at 1 h and 8 h after LPS injection were observed to assess whether the secretory diarrhea model was successfully established.The expression of CFTR gene segments of intestine tissue was de-tected by fluorescence quantitative PCR.Results LPS induced secretory diarrhea.CFTR gene was expressed in the mouse duodenum, jejunum, ileum and colon tissues with different expression abundance.It was highest in the colon, but the difference was not significant between intestinal segments.Compared with the control group, LPS up-regulated the tran-scription level of CFTR gene in the duodenum, jejunum and ileum, and down-regulated the transcription of CFTR gene in the colon.Conclusions The results of our study suggest that the changes of the transcriptional level of CFTR gene are closely related with the diarrhea induced by LPS and the effects in different intestinal segments on the diarrhea is different. The jejunum plays a crucial role and the colon plays a least role in the Cl-secretion.
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0.05). However, in 33%(3/9) patients with normal serum AFP (
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with social changing rapidly and the multiple-value in family therapy, family therapists gave up the exploration for the value forms and turned to study on the developing valuing. The value's evolution in the family therapy depends on interactions and base on evolving epistemology. The valuing course can be essentially defined as negotiation, which gives us the important suggestion for indigenous practice of family therapy.